Organocatalytic Asymmetric Synthesis and Use of Organoselenium Compounds

In the last ten years organocatalysis has emerged as an efficient and sustainable strategy for the asymmetric synthesis of chiral molecules. Optically active intermediates for novel interesting transformations are generated under mild and operationally simple conditions when selenium-containing compounds are used as reaction partners. The peculiar reactivity of organoselenium compounds has been exploited in practical one-pot sequences for the asymmetric construction of densely functionalized compounds starting from simple precursors. 1 Introduction 2 Organocatalytic Asymmetric Synthesis of alpha-Seleno Carbonyl Compounds and Applications 3 Organocatalytic Additions to Vinyl Selenones for the Enantioselective Construction of Quaternary Stereocenters 4 Concluding Remarks