Transition-Metal-Catalyzed Arylation of 1-Deazapurines via C-H Bond Activation

Transition-metal-catalyzed arylation of imidazo[4,5-b] pyridines (known as 1-deazapurines) is reported. 1-Deazapurines were synthesized from 5-aminoimidazoles, generated in situ by the reaction of methyl N-(cyanomethyl)formimidate with primary amines.