4.4 Article

A NHC-Involved, Cascade, Metal-Free, and Three-Component Synthesis of 2,3-Diarylated Fully Substituted Furans under Solvent-Free Conditions

期刊

SYNLETT
卷 -, 期 16, 页码 2420-2424

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1261229

关键词

NHC; fully substituted furans; umpolung; solvent-free synthesis; multicomponent reaction

资金

  1. Natural Science Foundation of the Jiangsu Higher Education Institutions [09KJA430003]
  2. Natural Science Foundation of Xuzhou City [XM09B016]
  3. Graduate Foundation of Xuzhou Normal University [2010YLB029]
  4. Qing Lan Project [08QLT001]

向作者/读者索取更多资源

An efficient synthesis of 2,3-diarylated fully substituted furans was performed through the sequential reactions of Knoevenagel reaction, Stetter reaction catalyzed by NHC, and intramolecular cyclization under solvent-free conditions. The protocol has the advantages of easy workup, high yields, and an environmental benign procedure compared with the reported methods.

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