期刊
SYNLETT
卷 -, 期 5, 页码 675-691出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1219369
关键词
gold catalysis; enantioselective catalysis; cycloisomerizations; alkynes; allenes
资金
- National Institute of General Medical Sciences [GM073932]
- Merck
- Boehringer-Ingelheim
- Amgen
- Dupont
- Eli Lilly
- GlaxoSmithKline
- Bristol-Myers Squibb
- Abbott
- Pfizer
- AstraZeneca
- Novartis
- Roche
Approaches to research in organic chemistry are as numerous as the reactions they describe. In this account, we describe our reactivity-based approach. Using our work in the area of gold catalysis as a background, we discuss how a focus on reaction mechanism and reactivity paradigms can lead to the rapid discovery of new synthetic tools.
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