期刊
SYNLETT
卷 -, 期 14, 页码 2164-2168出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1258495
关键词
aldehydes; cyanohydrins; green chemistry; multicomponent reaction; nucleophilic addition
资金
- National Natural Science Foundation of China [20772096]
- Key Laboratory of Eco-Environment-Related Polymer Materials (Northwest Normal University)
- Ministry of Education of China
An efficient method for one-pot three-component solvent-free cyanoaroylation of aldehydes using potassium hexacyanoferrate(II) as an environmentally benign cyanide source and triethylamine as a catalyst has been described. This method has advantages of not using strongly toxic cyanating agents and volatile organic solvents. In addition, the product was obtained in high yield using a simple workup procedure.
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