期刊
SYNLETT
卷 -, 期 14, 页码 2245-2248出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1217799
关键词
dimethoxytetrahydrofuran; iron; pyrrole; amine; water chemistry
资金
- MCINN [CTQ2006-10930]
- UCM-CAM [920234]
An operationally simple, practical, and economical protocol for iron(III) chloride catalyzed Paal-Knorr pyrrole synthesis in water in good to excellent yields has been developed. Several N-substituted pyrroles are readily prepared from the reaction of 2,5-dimethoxytetrahydrofuran and aryl/alkyl, sulfonyl and acyl amines under very mild reaction conditions
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