期刊
SYNLETT
卷 -, 期 4, 页码 599-601出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1219153
关键词
extremophile; total synthesis; natural product; heterocycle; thiazole
A total synthesis of the halophile-derived natural product (+)-bacillamide B is described. The route relies upon a Hantzsch synthesis of ethyl (S)-2-acetoxyethylthiazole-4-carboxylate followed by a dipyridyl disulfide-mediated coupling between the corresponding carboxylic acid and tryptamine. This synthesis has unambiguously demonstrated that in contrast to the previous tentative stereochemical assignments the stereochemistry of the alcohol at C15 of the title compound has S-configuration.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据