期刊
SYNLETT
卷 -, 期 7, 页码 975-978出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1072584
关键词
catalysis; indoles; alcohols; nucleophiles; alkylations
A Bronsted acid catalyzed C3-selective tert-alkylation of indoles using tertiary propargylic and benzylic alcohols has been developed. New C3-propargylated indole derivatives with a quaternary carbon at the propargylic position have been efficiently synthesized. Reactions were performed in air with undried solvents, and water was the only side product of the process.
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