Microwave enhancement of a 'one-pot' tandem azidation-'click' cycloaddition of anilines

The practical and efficient one-pot azidation of anilines with the reagent combination t-BuONO and TMSN3 has become a useful addition to the click-chemistry toolbox. Herein we report a modification of this methodology, using microwave radiation to significantly enhance the rate of fori-nation of 1,4-triazoles from in situ generated azides.