期刊
SYNLETT
卷 -, 期 16, 页码 2471-2474出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1078055
关键词
asymmetric organocatalysis; aldol reactions; biphasic aqueous catalysis; ionic-tagged proline; catalyst recycling
资金
- MIUR (Rome)
Imidazolium-tagged trans-4-hydroxy-L-proline, recently reported by us as an efficient catalyst for the asymmetric cross-aldol reaction in [bmim][Tf2N], gives much better results in terms of catalytic activity and stereochemical performance under aqueous biphasic conditions, providing aldols with anti/syn ratios up to 98:2 and ee (anti) up to 99%. The peculiar solubility properties of imidazolium-tagged trans-4-hydroxy-L-proline ensure an efficient separation of the product from the catalyst and the recycling of trans-4-hydroxy-L-proline for five times without appreciable loss of catalytic activity and stereochemical performance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据