期刊
SWISS MEDICAL WEEKLY
卷 140, 期 -, 页码 4-11出版社
E M H SWISS MEDICAL PUBLISHERS LTD
DOI: 10.4414/smw.2010.13042
关键词
adaptive and innate immunity; apoptosis; cathepsin; immune response; lysosome
资金
- Swiss National Science Foundation [310000-107526]
The immune system is composed of an enormous variety of cells and molecules that generate a collective and coordinated response on exposure to foreign antigens, called the immune response. Within the immune response, endo-lysosomal proteases play a key role. In this review we cover specific roles of cathepsins in innate and adaptive immunity, as well as their implication in the pathogenesis of several diseases.
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