期刊
SURVEY OF OPHTHALMOLOGY
卷 55, 期 4, 页码 386-392出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.survophthal.2010.02.002
关键词
copper deficiency; gastric bypass; myelopathy; optic neuropathy; vitamin B12 deficiency
We report two patients, both with a history of gastric surgery, who presented with progressive optic neuropathy and myelopathy. The patients' symptoms were initially attributed to vitamin B12 deficiency and/or neuromyelitis optica; however, after the neurologic deficits continued to progress with the use of conventional treatments, further evaluation was initiated, and a severe copper deficiency was revealed. Copper deficiency is a rare cause of progressive optic neuropathy and myelopathy and should be considered in the differential diagnosis. It is crucial to elicit a history of gastric surgery or other risk factors for hypocupremia in those patients undergoing an evaluation for subacute or chronically progressive optic neuropathy or myelopathy. (Surv Ophthalmol 55:386-392, 2010. (C) 2010 Elsevier Inc. All rights reserved.)
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