期刊
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
卷 33, 期 2, 页码 651-657出版社
SPRINGER
DOI: 10.1007/s00464-018-6408-5
关键词
Endoscopic submucosal dissection; ESD; Novel device; Articulating device; Standard endoscope; Colon
类别
Background and aimsColonic endoscopic submucosal dissection (ESD) is time-consuming and bears a high risk of perforation. The aim of the present study was to compare the safety and efficacy between novel articulating devices and conventional ESD in live porcine colon models.MethodsThirty ESDs in ten pigs were carried out at three different locations (15, 25, and 35cm from the anus) by the conventional method (n=15) and by the new method (n=15). Procedure times, adverse events (perforation, bleeding), and damage to the muscular layer were recorded, and the ESD time per unit area of the specimens was calculated.ResultsThe perforation rate using the conventional method was 6.7% (1/15), whereas that using the new method was 0.0%. The number of sites of muscular damage was significantly lower in the new than conventional method (6 vs. 37, respectively; P=0.024). The mean procedure time was significantly shorter in the new than conventional method (4.62.0 vs. 7.0 +/- 4.1min/cm(2), respectively; P=0.042).Conclusions Use of the new ESD method allows for reduced adverse events and a shortened resection time.
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