Unusual Presentations of Melanoma Melanoma of Unknown Primary Site, Melanoma Arising in Childhood, and Melanoma Arising in the Eye and on Mucosal Surfaces

Most melanomas present as primary tumors on the skin surface in adults; however, melanomas also arise in the eye and on the mucosal surfaces or present as apparently metastatic disease without any known history of a cutaneous primary. Melanoma is also being diagnosed during childhood more frequently than ever. Surgeons need to be aware of and understand these unusual presentations of melanoma to optimally manage their patients.