期刊
SURFACE & COATINGS TECHNOLOGY
卷 205, 期 5, 页码 1636-1641出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.surfcoat.2010.07.096
关键词
Sputtering; Antibacterial; Biocompatibility; TaN; Silver; Coating
Titanium-based materials have been used for dental implants due to their excellent biological compatibility, superior mechanical strength and high corrosion resistance. The osseointegration of titanium dental implants is related to their composition and surface treatment. A better anti-bacterial performance of the abutment seated in the prosthetic crown is beneficial for the osseointegration and for avoiding the infection after implantation surgery. In this study. TaN-Ag coatings with different Ag contents were deposited on a bio-grade pure Ti dental implant material. A twin-gun magnetron sputtering system was used for the deposition of TaN-Ag coatings. The Ag content in the deposited coatings was controlled by the magnetron power ratio of Ag/(Ta + Ag) targets. To verify the susceptibility of implant surface to bacterial adhesion, Staphylococcus aureus, one of the major pathogen frequently found in the implant-associated infections, was chosen for in vitro anti-bacterial analyses. In addition, the biocompatibility of human gingival fibroblast (HGF) cells on coatings was also evaluated. A composite structure of crystalline TaN and Ag nanoparticles was identified. The TaN-Ag coating with the highest Ag content of 21.4 at.% possessed the lowest bacterial retention and viability of S. aureus. From the MTT assay test, the mean optical density values for the TaN and TaN-Ag coated samples after 72 h of HGF adhesion were greater than the value obtained from the uncoated Ti. The results suggested that the TaN-Ag coatings improve antibacterial performance with compatible biological response. (C) 2010 Elsevier B.V. All rights reserved.
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