期刊
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE
卷 5, 期 1, 页码 -出版社
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/cshperspect.a023267
关键词
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资金
- NYU Kimmel Stem Cell Center
- NYSTEM training Grant [C026880]
- U.S. National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases [1R01AR59768-01A1]
- Ellison Medical Foundation
- NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES [R01AR059768] Funding Source: NIH RePORTER
The skin is a complex organ consisting of the epidermis, dermis, and skin appendages, including the hair follicle and sebaceous gland. Wound healing in adult mammals results in scar formation without any skin appendages. Studies have reported remarkable examples of scarless healing in fetal skin and appendage regeneration in adult skin following the infliction of large wounds. The models used in these studies have offered a new platform for investigations of the cellular and molecular mechanisms underlying wound healing and skin regeneration in mammals. In this article, we will focus on the contribution of skin appendages to wound healing and, conversely, skin appendage regeneration following injuries.
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