Intracranial Aneurysms Coiling With Matrix Immediate Results in 152 Patients and Midterm Anatomic Follow-Up From 115 Patients

Background and Purpose - We report our experience using Matrix coils in coiling of cerebral aneurysms. Methods - Clinical and angiographic outcomes of 152 patients (165 aneurysms) treated exclusively with Matrix coils were retrospectively analyzed. Results - There were 74 ruptured aneurysms (44.8%) and 91 unruptured (55.2%). After coiling, 84 (50.9%) aneurysms were occluded, 38 (23.0%) aneurysms had a neck remnant, and 43 (26.1%) aneurysms had a sac remnant. Packing ranged from 10% to 49% (mean and median, 27%). Overall treatment-induced morbidity was 6.6% and mortality was 1.3% (10 of 152 to 2 of 152, respectively). One hundred fifteen (69.7%) aneurysms were followed, disclosing 42 (36.5%) recurrences at a mean period of 9 months (median, 6 months; range, 1 to 28 months). The recurrence rate for small aneurysms (< 10 mm) was 28 (31.1%) of 90, whereas for larger aneurysms (>= 10 mm), the recurrence rate was 14 (56.0%) of 25 (P = 0.0336). When packing was <= 25%, the recurrence rate was 44.4%, whereas for aneurysms with packing <= 25%, the recurrence rate was 29.8% (P = 0.1588). Recurrence rate was not correlated to packing. Ruptured aneurysms recurred more frequently than unruptured aneurysms (P = 0.0004). Conclusion - Matrix coils provided no better recanalization rates than those reported previously for bare platinum coils. (Stroke. 2009; 40: 321-323.)