期刊
STRESS AND HEALTH
卷 27, 期 4, 页码 282-288出版社
WILEY
DOI: 10.1002/smi.1358
关键词
salivary alpha-amylase; psychological stress; sublingual saliva; circadian rhythm; sex difference
资金
- Japan Society for the Promotion of Science [20890239]
- Grants-in-Aid for Scientific Research [20890239] Funding Source: KAKEN
The salivary alpha-amylase (sAA) level is widely considered a marker of psychological stress. For clinical applicability, its characteristics should be examined under normal conditions. The aims of this study were to investigate the circadian rhythm, daily variation in a week and sex difference of the sAA level in sublingual saliva under a resting condition, for which 6 individuals, 11 individuals and 30 age-matched women and men, respectively, were enrolled. The individual sAA levels were measured once every hour from 10:00 to 16:00 (7 times/day); at 10:00 on Monday, Wednesday and Friday (thrice/week); and without any restriction in the respective experiments by using a hand-held sAA monitor. Repeated-measures analysis of variance and the Student's t-test were used for statistical analyses (p < 0.05). No significant differences in the sAA levels were observed among the different times of the day (p = 0.311) or different days of the week (p = 0.291), nor was a significant sex difference found (p = 0.962). These results suggest that the sAA level in sublingual saliva remains relatively stable under normal conditions and is not influenced by gender. It would be a useful tool to evaluate the effect of psychological stress in the clinical setting. Copyright (C) 2010 John Wiley & Sons, Ltd.
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