期刊
STEROIDS
卷 77, 期 11, 页码 1092-1100出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.steroids.2012.04.004
关键词
Pentacyclic steroids; Epoxide; Lactones; Amines; Thiols
We set out to describe an efficient and versatile method for preparing pentacyclic steroids diversely substituted at C-11 from cholic acid, via a stereoselective epoxidation and the epoxide opening as the key steps. The characteristic H-1 and C-13 NMR spectroscopic features of the synthesized compounds are reported. (C) 2012 Published by Elsevier Inc.
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