期刊
STEM CELLS AND DEVELOPMENT
卷 18, 期 6, 页码 807-812出版社
MARY ANN LIEBERT INC
DOI: 10.1089/scd.2009.0086
关键词
-
Intercellular communication participates in the regulation of normal hematopoiesis and possibly in neoplastic transformations in the hematopoietic niches. The role of gap junctions (GJs) and their connexins (Cxs) on hematopoietic tissues have been studied since the 1970s. Clearly, GJs are involved in different functional characteristics and connexin expression seems to be thoroughly regulated in hematopoietic tissues, suggesting that these molecules participate in the physiology of hematopoiesis. However, the exact mechanisms of GJs and Cxs are not characterized in detail. In this review we present the major findings of GJs and Cxs in normal hematopoietic tissues, and briefly discuss possible pathways of action and the potential of these molecules in hematopoietic reconstitution after cancer chemotherapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据