期刊
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
卷 129, 期 -, 页码 255-258出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.saa.2014.03.027
关键词
Acalypha indica; Antimicrobial; Biological method; Copper oxide nanoparticles; Cytotoxicity
类别
资金
- Association of Commonwealth Universities United Kingdom for the Commonwealth Academic Fellowship
- Association of Commonwealth Commission, United Kingdom for the Commonwealth Academic Fellowship
Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A. indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A. indica mediated copper nanoparticles was evaluated by MIT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity. (C) 2014 Elsevier B.V. All rights reserved.
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