期刊
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
卷 85, 期 1, 页码 288-292出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.saa.2011.10.011
关键词
QDs; CdS; Folic acid; Nanoparticles; Cell imaging
类别
资金
- Project of Shandong Province Higher Educational Science and Technology Program [J09LC66]
- Shandong Provincial Natural Science Foundation, China [ZR2010BL026, ZR2011BL026]
Synthesis of a highly dispersed hydrophilic CdS nanocrystals and their use as fluorescence labeling for live cell imaging is reported here. By carefully manipulating the surface of CdS nanocrystals, the dispersions of CdS-MAA-PEI-FA nanocrystals with high photostability is prepared. The receptor-mediated delivery of folic acid conjugated quantum dots into folate-receptor-positive cell lines such as CBRH7919 liver cancer cells was demonstrated by confocal microscopy. In the future. the further modified CdS nanoparticles can be used for the tissue imaging in vivo studies. Crown Copyright (C) 2011 Published by Elsevier B.V. All rights reserved.
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