Functionalized ZnS quantum dots as luminescent probes for detection of amino acids

In this work, L-cysteine capped-ZnS quantum dots were synthesized in aqueous medium, and their interaction with some of the amino acids was studied with fluorescence spectra. The results demonstrated that histidine could effectively quench the Quantum dots emission more than other amino acids. Electron transfer process between the capping ligands and histidine was mainly responsible for the remarkable quenching effect of histidine, because according to the structure of histidine, it is the strongest acceptor among essential amino acids. Under optimum conditions, the quenched fluorescence intensity increased linearly with the concentration of histidine ranging from 1.33 x 10(-6) to 1.49 x 10(-4) mol L-1. The limit of detection for histidine was 0.05 x 10(-7) mol L-1. Crown Copyright (C) 2012 Published by Elsevier B.V. All rights reserved.