相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。From Adaptive Licensing to Adaptive Pathways: Delivering a Flexible Life-Span Approach to Bring New Drugs to Patients
H-G Eichler et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2015)
FROM THE ANALYST'S COUCH Changes in clinical trial length
Lisette Pregelj et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Bringing in health technology assessment and cost-effectiveness considerations at an early stage of drug development
Bengt Jonsson
MOLECULAR ONCOLOGY (2015)
How long does biomedical research take? Studying the time taken between biomedical and health research and its translation into products, policy, and practice
Stephen R. Hanney et al.
HEALTH RESEARCH POLICY AND SYSTEMS (2015)
Accelerated Access to Innovative Medicines for Patients in Need
L. G. Baird et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2014)
IS THIS THE REAL LIFE? IS THIS JUST FANTASY?
David Grainger
INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE (2014)
FDA approvals usher in the post-interferon era in HCV
Cormac Sheridan
NATURE BIOTECHNOLOGY (2014)
Clinical development success rates for investigational drugs
Michael Hay et al.
NATURE BIOTECHNOLOGY (2014)
Emerging Viral Diseases: Confronting Threats with New Technologies
Hilary D. Marston et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
EU nations approve law to overhaul clinical trials
Rory Watson
BMJ-BRITISH MEDICAL JOURNAL (2013)
Diagnosing the decline in pharmaceutical R&D efficiency
Jack W. Scannell et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Regulatory Review of Novel Therapeutics - Comparison of Three Regulatory Agencies
Nicholas S. Downing et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Impact assessment of the European Clinical Trials Directive: a longitudinal, prospective, observational study analyzing patterns and trends in clinical drug trial applications submitted since 2001 to regulatory agencies in six EU countries
Markus Hartmann
TRIALS (2012)
Pharmaceutical Innovation in the 21st Century: New Drug Approvals in the First Decade, 2000-2009
K. I. Kaitin et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
Regulatory Science as a Bridge Between Science and Society
T. Tominaga et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
Evaluating Translational Research: A Process Marker Model
William Trochim et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2011)
The answer is 17 years, what is the question: understanding time lags in translational research
Zoe Slote Morris et al.
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE (2011)
The productivity crisis in pharmaceutical R&D
Fabio Pammolli et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies
LANCET (2008)
Are development times for pharmaceuticals increasing or decreasing?
S Keyhani et al.
HEALTH AFFAIRS (2006)
Estimating the cost of new drug development: Is it really $802 million?
CP Adams et al.
HEALTH AFFAIRS (2006)