期刊
SOFT MATTER
卷 9, 期 3, 页码 913-920出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2sm27163j
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资金
- U.S. Department of Energy, Office of Basic Energy Sciences, Division of Materials Sciences and Engineering [DE-FG02-07ER46463]
- National Center for Research Resources [5R21RR025801-03]
- National Institute of General Medical Sciences of the National Institutes of Health [8 R21 GM103388-03]
We propose a simple method to measure the viscoelasticity of hydrogels. Our method is based on twisting a flat-ended circular indenter on a thin layer of gel. Since poroelastic flow is suppressed under pure shear, such a method allows direct and separate measurement of the solid gel network's viscoelastic properties. A potential advantage of this method is that it is possible to carry it out in situ, e. g. under cell culture conditions, and with high-throughput. We use the correspondence principle to determine the relationship between the applied torque and the history of twist by solving an elasticity problem. A solution is obtained using the finite element and Hankel transform methods. The relation between the applied torque and the history of twist can be expressed in a simple closed-form expression involving the relaxation function of the gel, the thickness of the gel layer and the indenter radius.
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