期刊
SOFT MATTER
卷 7, 期 5, 页码 1581-1588出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0sm00862a
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资金
- Thuringian Ministry for Education, Science and Culture [B514-09051]
- Dutch Polymer Institute (DPI technology area HTE)
Nanoprecipitation is a facile, mild, and low energy input process for the preparation of polymeric nanoparticles. Basic requirements, as well as common techniques for the self-assembly of non-charged and non-amphiphilic macromolecules into defined nanoparticles are described. At present, the primary focus of polymer nanoprecipitation research lays on poly(lactic acid) (PLA) and its copolymer poly(lactic-co-glycolic acid) (PLGA). This contribution thus emphasises on polymers beyond PLA systems, such as common industrial-or tailored lab-made polymers, and their ability to form well-defined, functional nanoparticles for a variety of applications now and in the past two centuries. Moreover, in combination with high-throughput devices such as microfluidics, pipetting robots, inkjet printers, and automated analytical instrumentation, the abilities of nanoprecipitation may broaden tremendously with significant effects on new applications.
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