4.6 Article

Smart thermo-triggered squirting capsules for nanoparticle delivery

期刊

SOFT MATTER
卷 6, 期 16, 页码 3759-3763

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c002231d

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资金

  1. National Natural Science Foundation of China [20825622]
  2. National Basic Research Program of China [2009CB623407]
  3. Ministry of Education of China [200806100038]
  4. Sichuan Youth Science and Technology Foundation for Distinguished Young Scholars [08ZQ026-042]

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A squirting capsule is designed to deliver nanoparticles inspired by the squirting cucumber ejecting its seeds. The capsule has a thermo-sensitive hydrogel shell, and encapsulates nanoparticles by emulsifying the nanoparticle aqueous suspension in the water-in-oil emulsion core. The squirting capsule can completely squirt out the encapsulated nanoparticles with a high momentum, just like a nanoparticle bomb, by the dramatic shrinkage and sudden rupture of the capsule membrane upon heating.

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