期刊
SMALL
卷 9, 期 2, 页码 263-272出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.201201314
关键词
bionanotechnology; impalefection; copper oxide nanowires; cell membrane interactions
类别
资金
- NTNU
- NTNU NanoLab
- NorFab
- Danish Agency for Science, Technology and Innovation (The Danish Council for Strategic Research)
- Danish Agency for Science, Technology and Innovation (The Danish Natural Science Research Council)
- UNIK Synthetic Biology
A method to fabricate inexpensive and transparent nanowire impalement devices is invented based on CuO nanowire arrays grown by thermal oxidation. By employing a novel process the nanowires are transferred to a transparent, cell-compatible epoxy membrane. Cargo delivery and detailed cell-nanowire interaction studies are performed, revealing that the cell plasma membrane tightly wraps the nanowires, while cell membrane penetration is not observed. The presented device offers an efficient investigation platform for further optimization, leading towards a simple and versatile impalement delivery system.
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