期刊
SMALL
卷 6, 期 3, 页码 452-457出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.200901369
关键词
actin bundles; cargo transport; fascin; microchannels; myosin
类别
资金
- EPSCoR NSF
- Ministry of Education, Culture, Sports, Science, and Technology of Japan
The utilization of motor proteins for the movement and assembly of synthetic components is currently a goal of nanoengineering research. Application of the myosin actin motor system for nanotechnological uses has been hampered due to the low flexural rigidity of individual F-actin filaments. Here it is demonstrated how actin bundling can be used to affect the translational behavior of myosin-propelled filaments, transport molecules across a motor-patterned surface, and that the movement of bundled actin can be regulated photonically. These data suggest that actin bundling may significantly improve the applicability of the myosin motor for future nanotechnological applications.
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