Sleep disorders in patients with multiple sclerosis

Patients with multiple sclerosis (MS) often have Unrecognized sleep disorders at higher frequency than the general population. Sleep disorders such as sleep disordered breathing, insomnia, REM sleep behavior disorder, narcolepsy and restless legs syndrome have all been reported in the MS Population. Notably, the most common symptom of MS is fatigue, which itself has been correlated with sleep disturbances. Sleep disorders may impact the quality of life of the MS patient population. This paper reviews the association of sleep disorders with MS, and discusses the association of sleep disruption with MS fatigue. (C) 2009 Elsevier Ltd. All rights reserved.