期刊
SLEEP MEDICINE
卷 15, 期 7, 页码 833-839出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.sleep.2014.02.006
关键词
Sleep duration; Cholesterol; Triglyceride; Lipoprotein (a); Dyslipidemia; China Health and Nutrition Survey
资金
- National Institute of Nutrition and Food Safety, China Center for Disease Control and Prevention
- Carolina Population Center, University of North Carolina at Chapel Hill
- National Institutes of Health (NIH) [R01-HD30880, DK056350, R01-HD38700]
- Fogarty International Center, NIH
- China Japan Friendship Hospital
- Ministry of Health
Objective: To examine the associations between sleep duration and total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), apolipoprotein B (ApoB), apolipoprotein A1 (ApoA1), and lipoprotein (a) [Lp(a)]. Methods: The present study analyzed 8574 adults from the China Health and Nutrition Survey (2009). Sleep duration was classified into <= 6, 7, 8, 9, and >= 10 h. Age, education, occupation, current smoking, current drinking, physical activity, body mass index, hypertension, and diabetes were adjusted as confounders in gender-stratified multiple logistic regression models. Results: Compared with women reporting 8 h sleep duration, the odds ratios (ORs) and 95% confidence intervals (CIs) of high TC for those with <= 6, 7, 9, and >= 10 h were 1.65 (1.32-2.06), 1.19 (1.00-1.43), 1.11(0.89-1.39), and 1.27 (1.02-1.60) after adjusting for confounders. Likewise, the ORs (95% CIs) of high LDL-C were 1.71 (1.28-2.29), 1.36 (1.05-1.76), 1.04 (0.74-1.46), and 1.09 (0.78-1.53), whereas those of high ApoB were 1.80 (1.34-2.42), 1.15 (0.88-1.52), 0.95 (0.66-1.35), and 1.00 (0.70-1.43) for women with <= 6, 7, 9, and >= 10 h sleep duration, respectively. These associations were not statistically significant in men. Conclusions: Both shorter and longer sleep durations were associated with higher risks of abnormal serum lipid profiles in women but not in men. (C) 2014 Elsevier B.V. All rights reserved.
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