期刊
THERANOSTICS
卷 5, 期 2, 页码 150-172出版社
IVYSPRING INT PUBL
DOI: 10.7150/thno.9476
关键词
macrophages; theranostics; inflammation; phenotype; photodynamic therapy and photothermal therapy
资金
- NATIONAL INSTITUTE ON DRUG ABUSE [R21DA039621] Funding Source: NIH RePORTER
- NIDA NIH HHS [R21 DA039621] Funding Source: Medline
Inflammatory disease management poses challenges due to the complexity of inflammation and inherent patient variability, thereby necessitating patient-specific therapeutic interventions. Theranostics, which integrate therapeutic and imaging functionalities, can be used for simultaneous imaging and treatment of inflammatory diseases. Theranostics could facilitate assessment of safety, toxicity and real-time therapeutic efficacy leading to personalized treatment strategies. Macrophages are an important cellular component of inflammatory diseases, participating in varied roles of disease exacerbation and resolution. The inherent phagocytic nature, abundance and disease homing properties of macrophages can be targeted for imaging and therapeutic purposes. This review discusses the utility of theranostics in macrophage ablation, phenotype modulation and inhibition of their inflammatory activity leading to resolution of inflammation in several diseases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据