期刊
SLEEP AND BREATHING
卷 14, 期 2, 页码 109-114出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s11325-009-0290-2
关键词
ApneaLink; Sleep-disordered breathing; Sleep apnea; Obstructive sleep apnea; Screening
ApneaLink is a novel single-channel screening device for sleep apnea detection which is based on pressure-transduced measurement of oronasal airflow, summarised as respiratory disturbance index per hour of recording time (RDIApneaLink). We tested ApneaLink's diagnostic performance in a patient population with high prevalence of sleep apnea. ApneaLink was applied simultaneously with in-laboratory polysomnography (PSG) (n = 102, 24 female, age 54.7 years) and sequentially with PSG in the unattended home setting (n = 131, 37 female, age 59.1 years). Predictive values were computed for apnea-defining thresholds of apnea-hypopnea index (AHI)>= 5/h, >= 10/h, >= 15/h. Night-to-night variability (NNV) was assessed over three consecutive nights (n = 55, 10 female, age 48.9 years). RDIApneaLink correlated well with apnea-hypopnea index on PSG (PSG(AHI)) on simultaneous (r = 0.98, bias -0.7) and unattended home application (r = 0.95, bias -0.6). Predictive values were highest at AHI >= 10/h (in-laboratory: sensitivity 91.1%, specificity 87.5%, LR+ (positive likelihood ratio) 7.4, LR- 0.1; home: sensitivity 80%, specificity 85.5%, LR+5.5, LR- 0.2). NNV was low (V - 0.58 +/- 0.44, range 0 - 1.69). ApneaLink is an accurate screening tool for sleep apnea in a population with high prevalence of the disorder.
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