期刊
SKIN RESEARCH AND TECHNOLOGY
卷 14, 期 3, 页码 249-260出版社
WILEY
DOI: 10.1111/j.1600-0846.2008.00316.x
关键词
transdermal drug delivery systems; microneedles; needleless jet injectors; iontophoresis; liposomes
类别
Background: There are many advantages to administering drugs by routes that bypass the gastrointestinal tract. One such route is the transdermal in which the drug agent is applied to the skin in a patch or device of some type so that sufficient quantity penetrates the skin to exert a systemic effect. There are several theoretical advantages to this approach not the least of which is that the drug avoids being metabolized by the liver after absorption and that gastrointestinal irritation is avoided. Aims: To discuss the various ways in which drugs can be persuaded to cross the skin barrier and also to discuss the adverse effects of transdermal administration. Technical advances have permitted an increasing number of drugs to be offered in the transdermal format.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据