期刊
SKIN PHARMACOLOGY AND PHYSIOLOGY
卷 23, 期 -, 页码 17-27出版社
KARGER
DOI: 10.1159/000318264
关键词
Polihexanide, efficacy; Polihexanide, safety; Polihexanide, toxicology; Antiseptic; Wounds
资金
- B. Braun
- Lohmann Rauscher
- Serag-Wiesner
- Fresenius
Infected wounds are still one of the great challenges in medicine. In the last decade, it has become increasingly clear that antimicrobial chemotherapy is limited by the spread of antimicrobial resistance. Fortunately, new, highly effective antiseptic substances with a broad antimicrobial spectrum are available, so local treatment is expected to get increasingly more important in wound therapy. This paper reviews the antiseptic agent polihexanide (polyhexamethylene biguanide, PHMB), one of the most promising substances available today, from a clinical point of view, focusing on efficacy, safety and clinical applications. Copyright (C) 2010 S. Karger AG, Basel
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