4.5 Article

QUASI-STEADY STATE AND NEARLY INVARIANT SETS

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SIAM JOURNAL ON APPLIED MATHEMATICS
卷 70, 期 4, 页码 1341-1363

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SIAM PUBLICATIONS
DOI: 10.1137/090758180

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chemical reaction; time scale; Michaelis-Menten reaction

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We propose the notion of nearly invariant set for an ordinary differential equation to give a clear mathematical meaning to the notion of quasi-steady state (QSS) in equations describing chemically reacting systems. We show that this approach is sensible in view of the intended applications. Moreover, the approach leads to a heuristic for finding small parameters to satisfy a QSS assumption. The results are illustrated by several examples.

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