期刊
SCIENTIFIC REPORTS
卷 5, 期 -, 页码 -出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/srep09686
关键词
-
资金
- PRESTO, JST
- CREST, JST
- [22121003]
- [25117711]
- [25112505]
- [24247014]
- [25293057]
- [26640038]
- [25650018]
- [24570126]
- [24687012]
- Grants-in-Aid for Scientific Research [22121003] Funding Source: KAKEN
Selective binding between pre- and postsynaptic adhesion molecules can induce synaptic differentiation. Here we report the crystal structure of a synaptogenic trans-synaptic adhesion complex between Slit and Trk-like family member 2 (Slitrk2) and receptor protein tyrosine phosphatase (RPTP) delta. The structure and site-directed mutational analysis revealed the structural basis of splicing-dependent adhesion between Slitrks and type IIa RPTPs for inducing synaptic differentiation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据