Pt-CuO nanoparticles decorated reduced graphene oxide for the fabrication of highly sensitive non-enzymatic disposable glucose sensor

Platinum nanocubes and copper oxide nanoflowers decorated reduced graphene oxide (rGO) obtained by one step chemical process. X-ray crystallographic analysis confirms that CuO in monoclinic form and Pt in cubic crystal form. Pt-CuO/rGO nanocomposite dispersed in N,N-dimethylformamide (DMF) was drop casted onto the working electrode of an indigenously fabricated screen printed three electrode system. Oxidation of glucose on the Pt-CuO/rGO nanocomposite modified screen printed electrode (SPE) was occurred at +0.35 V. The sensor showed a limit of detection 0.01 mu M (S/N = 3) and very high sensitivity of 3577 mu A mM(-1) cm(-2) with linear response upto 12 mM. The sensor was highly selective to glucose in the presence of commonly interfering species like ascorbic acid (AA), dopamine (DA), uric acid (UA) and acetaminophen. The sensor was employed for the testing of glucose in blood serum and the results obtained were comparable with other standard test methods. (C) 2014 Elsevier B.V. All rights reserved.