期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 185, 期 -, 页码 720-724出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2013.05.053
关键词
Biothiol; Coumarin; Disulfide bond; Fluorescence; Ratiometric
资金
- Hankuk University of Foreign Studies
We report an aminocoumarine-based fluorescent probe (1) possessing a disulfide group to detect biothiols in HEPES buffer. Prominent ratiometric fluorescence changes of the probe are induced by the disulfide bond cleavage of 1 upon the addition of biothiols. The ratiometric probe (1) exhibits both high sensitivity and selectivity toward amino acids containing a thiol group over other various amino acids in water. (C) 2013 Elsevier B.V. All rights reserved.
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