期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 173, 期 -, 页码 908-913出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2012.07.045
关键词
Lab-on-a-chip; Tumor spheroid; Long-term cell culture; Three-dimensional microfluidic system
资金
- European Union
- [UDA-POIG.01.03.01-00-014/08-01]
In this paper, we present a low-cost three-dimensional microfluidic system made of poly(dimethylsiloxane) for tumor spheroid formation and cultivation. Tumor spheroids reaching diameters of up to 300 mu m were cultured in perfusion microchambers providing extremely low shear stress. Spheroids were cultured for 15 days and high viability of the cells was observed within this time. The presented microsystem is a prospective solution for development of microfluidic platforms for anticancer drug screening. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据