期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 156, 期 1, 页码 332-337出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2011.04.042
关键词
Fluorescent probe; PET; ESIPT; 3-Hydroxyflavone derivative; Thiol probe
资金
- Chinese Academy of Sciences
- NNSF of China [21073213, 20673132, 20903110]
- Research Grants Council of the Hong Kong SAR [CityU 123607]
- 863 Program [2009AA03Z318]
- National Basic Research Program of Chin [2007CB936001]
We have developed a conceptually new design strategy for fluorescent probes based on a combinational use of photo-induced electron transfer (PET) and excited-state intramolecular proton transfer (ESIPT) mechanisms. This turn-on fluorescence thiol-probe shows fast responses to mercapto-biomolecules with high sensitivity and selectivity. Furthermore, it was used for imaging in living cells with excellent performance. (C) 2011 Elsevier B.V. All rights reserved.
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