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DIABETES (2015)
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DIABETES (2015)
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CELL METABOLISM (2014)
Islet cell plasticity and regeneration
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MOLECULAR METABOLISM (2014)
Adult Duct-Lining Cells Can Reprogram into β-like Cells Able to Counter Repeated Cycles of Toxin-Induced Diabetes
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DEVELOPMENTAL CELL (2013)
NeuroD1 A45T and PAX4 R121W polymorphisms are associated with plasma glucose level of repaglinide monotherapy in Chinese patients with type 2 diabetes
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BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2012)
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WT1 and Pax2 Re-Expression Is Required for Epithelial-Mesenchymal Transition in 5/6 Nephrectomized Rats and Cultured Kidney Tubular Epithelial Cells
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CELLS TISSUES ORGANS (2012)
Subpopulations of GFP-Marked Mouse Pancreatic β-Cells Differ in Size, Granularity, and Insulin Secretion
Hitoshi Katsuta et al.
ENDOCRINOLOGY (2012)
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
Yoon Shin Cho et al.
NATURE GENETICS (2012)
The Adult Mouse and Human Pancreas Contain Rare Multipotent Stem Cells that Express Insulin
Simon R. Smukler et al.
CELL STEM CELL (2011)
In Vivo Conditional Pax4 Overexpression in Mature Islet β-Cells Prevents Stress-Induced Hyperglycemia in Mice
Kai Hui Hu He et al.
DIABETES (2011)
A Novel PAX4 Mutation in a Japanese Patient with Maturity-Onset Diabetes of the Young
Wakako Jo et al.
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE (2011)
beta-Cell Growth and Regeneration: Replication Is Only Part of the Story
Susan Bonner-Weir et al.
DIABETES (2010)
Reciprocal modulation of adult beta cell maturity by activin A and follistatin
M. Szabat et al.
DIABETOLOGIA (2010)
Expansion of beta-cell mass in response to pregnancy
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TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells
Patrick Collombat et al.
CELL (2009)
Adaptive β-cell Proliferation Is Severely Restricted With Advanced Age
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DIABETES (2009)
Maturation of Adult β-Cells Revealed Using a Pdx1/Insulin Dual-Reporter Lentivirus
Marta Szabat et al.
ENDOCRINOLOGY (2009)
Candidate gene polymorphisms for diabetes mellitus, cardiovascular disease and cancer are associated with longevity in Koreans
Ji Wan Park et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2009)
P21cip-Overexpression in the Mouse β Cells Leads to the Improved Recovery from Streptozotocin-Induced Diabetes
Jie Yang et al.
PLOS ONE (2009)
Perplexing Pax: From Puzzle to Paradigm
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DEVELOPMENTAL DYNAMICS (2008)
A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells
Kerstin Wellershaus et al.
EXPERIMENTAL CELL RESEARCH (2008)
The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1
Thierry Brun et al.
HUMAN MOLECULAR GENETICS (2008)
A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease
Thierry Brun et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2008)
Pax4 paired domain mediates direct protein transduction into mammalian cells
Jun Lu et al.
ENDOCRINOLOGY (2007)
PAX4 mutations in Thais with maturity onset diabetes of the young
Nattachet Plengvidhya et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells
T. Brun et al.
ONCOGENE (2007)
Growth and regeneration of adult β cells does not involve specialized progenitors
Monica Teta et al.
DEVELOPMENTAL CELL (2007)
Notch signaling reveals developmental plasticity of Pax4+ pancreatic endocrine progenitors and shunts them to a duct fate
Amy L. Greenwood et al.
MECHANISMS OF DEVELOPMENT (2007)
Aberrant DNA demethylation in promoter region and aberrant expression of mRNA of PAX4 gene in hematologic malignancies
Yinghua Li et al.
LEUKEMIA RESEARCH (2006)
The Arg121Trp variant in PAX4 gene is associated with beta-cell dysfunction in Japanese subjects with type 2 diabetes mellitus
Y Tokuyama et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2006)
Pax6 is required for production and maintenance of progenitor cells in postnatal hippocampal neurogenesis
M Maekawa et al.
GENES TO CELLS (2005)
Very slow turnover of β-cells in aged adult mice
M Teta et al.
DIABETES (2005)
The diabetes-linked transcription factor PAX4 promotes β-cell proliferation and survival in rat and human islets
T Brun et al.
JOURNAL OF CELL BIOLOGY (2004)
PAX4 gene variations predispose to ketosis-prone diabetes
F Mauvais-Jarvis et al.
HUMAN MOLECULAR GENETICS (2004)
Induction of beta-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D-1
I Cozar-Castellano et al.
DIABETES (2004)
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
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NATURE (2004)
DNA sequence motifs conserved in endocrine promoters are essential for Pax4 expression
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DEVELOPMENTAL DYNAMICS (2003)
Dominant role of the niche in melanocyte stem-cell fate determination
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NATURE (2002)
Expression of dominant negative form of PAX4 in human insulinoma
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Sialylated form of the neural cell adhesion molecule (NCAM) -: A new tool for the identification and sorting of β-cell subpopulations with different functional activity
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DIABETES (2001)
Pax4 regulatory elements mediate beta cell specific expression in the pancreas
C Brink et al.
MECHANISMS OF DEVELOPMENT (2001)
Pax7 is required for the specification of myogenic satellite cells
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CELL (2000)
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