期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 134, 期 2, 页码 816-821出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2008.06.027
关键词
Nanogold; Single walled carbon nanotubes; Serotonin; 5-Hydroxyindole acetic acid; Voltammetry
资金
- Council of Scientific and Industrial Research [9/143(570)07 EMR-I]
- MHRD
- CSIR, New Delhi [01/2045/06-EMR-II]
Simultaneous voltammetric determination of serotonin and 5-hydroxyindole acetic acid has been described at single walled carbon nanotube modified glassy carbon electrode and gold nanoparticles modified indium tin oxide electrode. The method described is fast, simple, accurate with detection limits as low as 32 nM for 5-hydroxytryptamine (5-HT) at single-walled carbon nanotube modified glassy carbon electrode and 27 nM for 5-hydroxyindole acetic acid (5-HIAA) at gold nanoparticles modified indium tin oxide electrode. Linear variation of peak current with change in concentration was observed in the concentration range 0.1 - 100 mu M for 5-HT and 5-HIAA. Application of the method for non-invasive determination of the compounds in urine samples has also been described. The inter- and intra-day stability of the electrodes were also determined and electrodes were found to be sufficiently stable for 1 week. (C) 2008 Elsevier B.V. All rights reserved.
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