期刊
SENSORS AND ACTUATORS A-PHYSICAL
卷 196, 期 -, 页码 1-7出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.sna.2013.03.028
关键词
Surface acoustic wave; Mixing; IDT; Microfluidic channel
Many applications need fast and efficient mixing of the sample and reagent with high throughput in a microfluidic channel. Due to low Reynolds number, mixing based on molecular diffusion plays an important role in a microfluidic channel. However, the diffusion based mixing process is very slow and the efficiency is low. The development of a highly efficient mixing technique is essential for lab-on-a-chip and micro-total-analysis systems. In this paper, we introduce a highly efficient active mixing technique using dual acoustic streaming field induced by surface acoustic waves in a microfluidic channel. The rapid and high efficiency active mixing of a fluorescent dye solution and deionized water in a microfluidic channel was demonstrated with single acoustic excitation by one interdigitated transducer (IDT) as well as dual excitation by two IDTs. The mixing efficiencies were investigated as a function of applied voltage and flow rates. Our results indicate that with the same operation parameters, the mixing efficiency with dual-IDT design increased to 96.7% from 69.8% achievable with the traditional single-IDT design. The effect of aperture length of the IDT on mixing efficiency was also investigated. (c) 2013 Elsevier B.V. All rights reserved.
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