4.6 Review

Conductometric microbiosensors for environmental monitoring

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SENSORS
卷 8, 期 4, 页码 2569-2588

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MOLECULAR DIVERSITY PRESERVATION INT
DOI: 10.3390/s8042569

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interdigitated microelectrodes; conductometric measurements; enzymatic microsensors; whole-cell microsensors; pesticides; herbicides; TOC; nitrate; heavy metals; toxicity assessment

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This review presents the principles of conductometric measurements in ionic media and the equivalent electrical circuits of different designs for conductometric measurements. These types of measurements were first applied for monitoring biocatalytic reactions. The use of conductometric microtransducers is then presented and detailed in the case of pollutant detection for environmental monitoring. Conductometric biosensors have advantages over other types of transducers: they can be produced through inexpensive thin-film standard technology, no reference electrode is needed and differential mode measurements allow cancellation of a lot of interferences. The specifications obtained for the detection of different pesticides, herbicides and heavy metal ions, based on enzyme inhibition, are presented as well as those obtained for the detection of formaldehyde, 4-chlorophenol, nitrate and proteins as markers of dissolved organic carbon based on enzymatic microbiosensors.

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