期刊
SEMINARS IN THROMBOSIS AND HEMOSTASIS
卷 36, 期 8, 页码 881-887出版社
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0030-1267042
关键词
Microparticle; platelet; megakaryocyte; cytoskeleton
资金
- NHLBI NIH HHS [R01 HL068130] Funding Source: Medline
Platelet microparticles are the most abundant cell-derived microparticle subtype in the circulation. Yet the mechanism by which platelet microparticles are formed is poorly defined. This review highlights the concept of the generation of microparticles from platelets and their precursor cells, megakaryocytes. Special emphasis is placed on the mechanisms of microparticle formation and novel functions for microparticles in normal physiology and disease states.
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