期刊
SEMINARS IN THROMBOSIS AND HEMOSTASIS
卷 36, 期 8, 页码 819-823出版社
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-0030-1267035
关键词
Microparticles; impedance-based flow cytometry; tissue factor bearing microparticles; Coulter principle
资金
- NIH [K23 HL084052]
Over the last several years, there has been considerable interest in evaluating the biological relevance of alterations in blood-borne microparticle populations. The most commonly employed technique for the characterization of microparticles is light scatter flow cytometry. However, the enumeration and sizing of submicron particles based on light scattering properties can be problematic. Impedance-based flow cytometry based on the Coulter principle offers a sensitive methodology to characterize microparticles. This review details the rationale for employing impedance-based flow cytometry in the measurement of blood-borne microparticles.
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