期刊
SEMINARS IN IMMUNOPATHOLOGY
卷 33, 期 1, 页码 67-87出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00281-010-0204-1
关键词
Type 1 diabetes; NOD mice; Immunological tolerance; Genetics
For almost 30 years, the non-obese diabetic (NOD) mouse has served as the primary model for dissecting the genetic and pathogenic basis for T-lymphocyte-mediated autoimmune type 1 diabetes (T1D). However, while sharing many similarities, it is becoming increasingly appreciated that there are also some differences in the immunopathogenic basis of T1D development between humans and NOD mice. This review will focus on aspects of T1D development in NOD mice that are similar and different from that in humans.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据