期刊
SEMINARS IN FETAL & NEONATAL MEDICINE
卷 14, 期 3, 页码 151-156出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.siny.2008.10.003
关键词
Antenatal corticosteroid therapy; Betamethasone; Dexamethasone; Fetal movement; Fetal heart rate; Heart rate variability; Doppler velocity waveforms
类别
Antenatal corticosteroid therapy to enhance fetal lung maturity in threatened preterm delivery has a number of non-pulmonary side-effects, both beneficial and undesirable. This review focuses on the short-term (transient) effects of betamethasone and dexamethasone on aspects of fetal circulation and behaviour which are used clinically as markers of fetal well-being. We summarise the effects observed, discuss the proposed underlying mechanisms, and emphasise the consequences for clinical decision-making. Recommendations are given to optimise medical care and to minimise the risk of unwarranted iatrogenic preterm delivery. (C) 2008 Elsevier Ltd. All rights reserved.
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