期刊
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
卷 30, 期 -, 页码 55-64出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcdb.2013.11.002
关键词
Tubulobulbar complex; Junction endocytosis; Sperm release; Spermatocyte translocation
资金
- NSERC [155397-13]
Tubulobulbar complexes are elaborate clathrin/actin related structures that form at sites of intercellular attachment in the seminiferous epithelium of the mammalian testis. Here we summarize what is currently known about the morphology and molecular composition of these structures and review evidence that the structures internalize intercellular junctions both at apical sites of Sertoli cell attachment to spermatids, and at basal sites where Sertoli cells form the blood-testis barrier. We present updated models of the sperm release and spermatocyte translocation mechanisms that incorporate tubulobulbar complexes into their designs. Crown Copyright (C) 2013 Published by Elsevier Ltd. All rights reserved.
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